Endocrine Abstracts

Introduction: Prevalence of vitamin D deficiency is well recognised and public awareness is being raised to encourage intake of vitamin D supplements. Optimal serum concentration of 25OHD for bone and general health has not been established. Desirable serum concentration of 25OHD had been proposed as >75 nmol/l and levels above 500 nmol/l are deemed toxic. Guidance is available on tolerable upper limit of vitamin D intake by US Institute of Medicine....

A 3-year-old boy born to non-consanguineous parents. He was diagnosed to have autism at 2 years of age. He had a history of pica. He was admitted with severe carpopedal spasms of hands and feet. Investigations revealed severe hypomagnesaemia, hypocalcaemia, hypokalaemia, hyponatremia, and moderately low vitamin D levels. Parathyroid hormone concentration was low. Urine analysis revealed loss of sodium, calcium, magnesium and sodium. Renal functions and renal ultrasound were no...